ncRNA name | PKCβ shRNA |
ncRNA Category | shRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | UM cell lines Mel202, Omm1.3, C918 and Mel285 |
Methods | shRNA knockdown, MTS proliferation assay |
Expression pattern | associated |
Functional description | Expression of PKCβ, PKCθ or PKCε shRNA significantly decreased viability of Mel202 and Omm1.3 cells (Figure 8D). A reduction in viability was also seen in C918 cells expressing shRNA of PKCβ, PKCε or PKCθ and in Mel285 cells expressing PKCβ or PKCθ. |
PubMed ID | 22253748 |
Year | 2012 |
Title | The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanoma. |
Drug-related ncRNA | NA |
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